FlowCam^® - Flow Imaging Microscopy Blog

Join us in Boston next week (booth #700) for the BioProcess International conference. This event represents our first combined marketing effort in the Life Sciences sector since our acquisition in 2020.

Flow Imaging Microscopy is currently recommended by the USP as an orthogonal analytical method for biopharmaceuticals. It has yet to be integrated into every drug development and testing laboratory however. Integrating new technologies upstream in the formulation development process continues to be an essential path for improving the safety and efficiency of the drug development. Once new methods and technologies are proven and accepted upstream, it's possible to pave the way for new technologies to be implemented downstream and beyond. 

Hundreds of biopharmaceutical and pharmaceutical companies worldwide are now using the FlowCam to improve the quality, safety and stability of their formulations. Since most teams purchasing an analytical instrument for their lab want to read studies conducted by other scientists, we have gathered a collection of the top influential studies using the FlowCam to demonstrate how they are integrating Flow Imaging Microscopy into their research.

Application to a therapeutic protein pumping study performed at Skagg School of Pharmacy and Pharmaceutical Sciences

Sub-visible particle characterization is a critical method for assessing drug substance and drug product quality and stability. In this study, we evaluated the capabilities of the new FlowCam Nano (which utilizes patented oil immersion flow microscopy), in conjunction with a peristaltic pumping study that focused on protein particle formation generated during filling pump operations.

The FlowCam was recently used by a team led by Natasha Barteneva of Nazarbayev University to develop a method for the classification of Microcystis colonial morphospecies in samples obtained from a long-term mesocosm experiment (the AQUACOSM Lake Mesocosm Warming Experiment).

Yokogawa Fluid Imaging partner, Axel Wilde of ANASYSTA, recently wrote an article discussing the acquisition of Fluid Imaging Technologies by Yokogawa, and how the FlowCam compliments Yokogawa's current product portfolio. Keep reading, or check out the article on Yokogawa's Life Innovation Blog.

Last week, The-Scientist.com introduced their new Research Products blog. Their very first post discusses the capabilities of the FlowCam Nano:

The FlowCam Aquatic Research Equipment & Travel Grant is back by popular demand for the 2021-22 academic year. This equipment grant provides an opportunity for one graduate student and up to two undergraduate faculty members to receive the use of a FlowCam for the semester of their choice.

Graduate applicants are eligible for a FlowCam 8000 (8100 or 8400) and undergraduate applicants are eligible for a FlowCam 5000.

Pictured here: Drs. Kerry Whittaker (left) and LeAnn Whitney (right) of Maine Maritime Academy (MMA), winners of the 2020 FlowCam Undergraduate Grant.

Back by popular demand, the FlowCam Student Equipment Grant program has a new category specifically for undergraduate institutions. The recipients of this inaugural undergraduate grant were Drs. Kerry Whittaker, LeAnn Whitney, and Steven Baer of the Corning School of Ocean Studies at Maine Maritime Academy (MMA), a small college of about 950 students located in Castine, ME.

Have you ever wondered how our technical customer support team performs quality control checks during services and before shipping new instruments? Here's one example of the process our team uses to check for accuracy on the FlowCam Cyano.

Pictured here: Enterprise Pond at YFT headquarters in Scarborough, Maine. The source of the sample used in this demonstration.

An interview with Steve Bowen, Director of Sales, Yokogawa Fluid Imaging Technologies

What is particle analysis?

Particle analysis involves taking a sample of a substance and analyzing the individual particles of the sample. The basic goal is to determine the constituents of a mixture and to differentiate between particles in the sample. Typical measurements of particles that are of interest include: particle size distribution, particle count, various measurements of particle shape, and particle concentration.