FlowCam® - Flow Imaging Microscopy Blog

Cybele Brooks

Recent Posts

FlowCam and the BR1000 Together at BioProcess International Boston

Join us in Boston next week (booth #700) for the BioProcess International conference. This event represents our first combined marketing effort in the Life Sciences sector since our acquisition in 2020.

Read More

Topics: Protein Therapeutics, FlowCam Technology, Biopharmaceutical Research

FlowCam Used to Study Intravitreal Anti-VEGF Drugs: Particle Burden and Protein Aggregates

In a recent paper discussing particle counting and analytical techniques, the number and type of particles present in intravitreal injection formulations of three different drug agents used against vascular endothelial growth factor were investigated.

Read More

Topics: Protein Therapeutics, Biopharmaceutical Research, Nanoparticles

5 Considerations When Adding Liquid Handling Automation to your Biopharmaceutical Lab

Biopharma labs today are looking for ways to improve accuracy, safety and productivity. The use of robotics to enable the unattended, continuous running of samples is gaining popularity. The following post can help you determine if an automated liquid handling system can help your formulation development lab attain the goals of reproducibility, traceability and flexibility.

Read More

Topics: Industrial Applications, Protein Therapeutics, Biopharmaceutical Research

Bioprocessing Summit in Boston this Week - Discussions on Quality & Stability of Biologics

This week the Bioprocessing Summit is happening in Boston and virtually.

The popular 9th Annual Rapid Methods to Assess Quality & Stability of Biologics conference track will bring together experts in analytical and formulation development to discuss rapid and practical ways to accelerate prediction and screening for protein instabilities in early- and late-stage development. The conference features case studies, unpublished work on new methods and tools employed in real-time and accelerated stability studies for proteins, cell and gene therapy products, high-throughput analytics, developability assessment, high-throughput analytics, multi-attribute methods, post-translational modifications, and stability in vaccines.

Read More

Topics: Protein Therapeutics, User Spotlight, Biopharmaceutical Research

FlowCam - Flow Imaging Microscopy (FIM) Guides Forced Degradation of Cell-based Medicinal Products (CBMP)

Cell-based medicinal products (CBMPs) offer promising opportunities for the treatment of diseases with previously limited or no therapeutic options. However, the complexity and intrinsically fragile nature of these CBMPs create significant challenges in formulation development, analytical characterization, manufacturing, and stability assessment.

This recent study used a FlowCam, Flow Imaging Microscope (FIM) assisted by machine learning software, to measure cell viability and concentration, and to quantify debris particulates. These particulates were the result of forced degradation studies that mimic conditions from cell procurement to administration of product. In particular, the effects of freeze-thawing and shaking on CBMPs were studied. Read More

Topics: Protein Therapeutics, Biopharmaceutical Research

FlowCam at the National Marine Educators Association (NMEA) Conference

Earlier this month, Savannah Judge, one of our Aquatic Markets Experts, co-presented with Kerry Whittaker and LeAnn Whitney of The Corning School of Ocean Studies at Maine Maritime Academy in Castine, ME. The topic of the presentation was "Use of high-throughput fluid imaging technology in the field-based undergraduate ocean classroom with FlowCam".

Read More

Topics: Marine Research, News and Events, User Spotlight, Aquatic Research

Research Paper Uses FlowCam to Study Protein Aggregation in Intravenous Drugs Resulting from External Stressors

There continue to be ongoing concerns about post-manufacture particulate formation in biopharmaceutical drug products. The stresses, which induce particle formation in IV infusion bags, are suspected to be related to the type of diluent (i.e., saline or dextrose).

Read More

Topics: Protein Therapeutics, Biopharmaceutical Research

City of Worcester Will Integrate FlowCam Cyano for Proactive Water Quality Monitoring

The City of Worcester, MA has purchased a FlowCam Cyano to help expand a volunteer water quality monitoring program. The effort is led by Jacquelyn Burmeister, a senior environmental analyst with the City's Lakes & Ponds Program. Together with several other local watershed associations, she helped organize a regional cyanobacteria monitoring collaborative that has recruited dozens of volunteers to help expand cyanobacteria monitoring in the area's recreational waters.

Read More

Topics: Invasive Species, Harmful Algal Blooms, Municipal Water (Drinking/Wastewater)

FlowCam Reveals Silicone Oil Droplets and Other Particulates in Intravitreal Injections (IVIs)

Silicone oil has long been used in the pharmaceutical industry as a lubricant for syringes. It serves to reduce the force necessary to depress the plunger, and can make procedures more comfortable and safer for the doctor and patient as it allows the needle to slide more easily through the eye wall.

Read More

Topics: Protein Therapeutics, Biopharmaceutical Research

Over 1000 FlowCam Instruments, in More Than 60 Countries, and on Every Continent: Making the World a Safer Place.

Earlier this month Yokogawa Fluid Imaging Technologies sold its 1,000th FlowCam instrument. “I am so proud of what our company has achieved since being founded in 1999”, commented Kent Peterson, company CEO. “We started our company in a garage in East Boothbay, and today we can proudly say there are over 1,000 FlowCam instruments being used in over 60 countries”.

Pictured here: Ilmars Labrencis, Yokogawa Fluid Imaging Director of Operations (the one responsible for getting all of those FlowCams out the door to our customers), rings the bell for the sale of the 1000th FlowCam!

Read More

Topics: News and Events