FlowCam - Flow Imaging Microscopy Blog

Water Quality Monitoring Workshop to be Offered at AWWA ACE Conference

After a two-year break, the American Water Works Association's ACE Conference will be hosted in-person in San Antonio, Texas, from June 12th - 15th. The conference brings together water sector professionals from around the country to learn about new technologies and techniques in water quality monitoring, mitigation strategies, and overcoming engineering challenges. 

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Topics: Freshwater Research, News and Events, Harmful Algal Blooms, Municipal Water (Drinking/Wastewater), User Spotlight, Aquatic Research

Obtaining Accurate Concentration Data with FlowCam

FlowCam 8000 series instruments provide count and concentration data for a wide variety of fluid samples. Relative counts can be compared reliably among different samples, while concentrations provide particles/mL values based on the actual fluid volume imaged by the instrument. By understanding and considering the various factors that can affect reported concentrations, FlowCam users can ensure they are obtaining accurate concentration data.

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Topics: FlowCam Technology

Recent Notable FlowCam Studies in Aquatic Research

Collage for blog and socialScientists from around the world have been using FlowCam for over 20 years to better understand the ecosystems in our lakes, rivers, and oceans.

As new research is published, we continue to review the literature where FlowCam is utilized for essential and innovative studies in aquatic research. The publications included in our most recent list showcase important FlowCam applications in marine and freshwater research.

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Topics: Marine Research, Freshwater Research, Harmful Algal Blooms, Aquatic Research

Meet FlowCam's World Class Customer Care Team

When you buy a FlowCam, it's more than just an instrument for your lab. It represents a partnership! You join our FlowCam family and gain access to our team of technical experts dedicated to supporting and improving your FlowCam and VisualSpreadsheet experiences.

We build personal relationships with our customers and are here to support you every step of the way.  Your success is our goal, and we're thrilled to help you make more effective medicines, ensure clean drinking water, monitor the health of our water bodies/ecosystems, and make safer products. As your partner, we offer virtual and in-person installation and training, IQ/OQ services, method development, and other resources to help you accomplish your analysis goals. 

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Topics: News and Events

FlowCam Education an Important Part of 2022 Joint Aquatic Sciences Meeting

This May, nine aquatic science organizations will come together in person to host the largest aquatic science conference in history. The 2022 Joint Aquatic Sciences Meeting "is designed to bring together deep, multidisciplinary subject-matter expertise to collaboratively educate one another and solve the complex environmental problems facing our society and our planet today".

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Topics: Marine Research, Freshwater Research, News and Events, Harmful Algal Blooms, Aquatic Research

FjordFlux Cruise Uses FlowCam to Analyze Glacier Particles and Assess Effects of Climate Change

FlowCam user, Jochen Wollschläger, of Germany's University of Oldenburg, recently returned from a research trip aboard the RV METEOR as part of the FjordFlux Cruise in the Beagle Channel, at the southernmost tip of Chile and Argentina. The goal of the expedition was to utilize the fjords of Patagonia to better understand how climate change will affect similar environments in Antarctica. Carried out in the context of the DYNAMO Project, the cruise was a cooperation between Germany, Chile, and Argentina. 

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Topics: Marine Research, User Spotlight, Aquatic Research

Top FlowCam Studies for Biopharmaceuticals

Flow Imaging Microscopy (FIM) has emerged as an essential tool and an increasingly common approach in analytical labs for the quantification and characterization of particles in biotherapeutics. The body of scientific research using FlowCam technology to analyze biotherapeutic samples is continuing to grow and expand. 

These publications not only demonstrate the utility of FlowCam in biotherapeutic development and manufacturing but highlight exciting new applications for FlowCam such as artificial intelligence-based particle analysis as well as cell and gene therapy development.

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Topics: Protein Therapeutics, News and Events, Biopharmaceutical Research

Automated Liquid Handling to Streamline Your FlowCam Workflow

The new ALH for FlowCamTM Automated Liquid Handling system is ready for deployment in your lab. Automated liquid handlers (ALHs) use robotics to perform sample processing and analysis with minimal human intervention. Automation reduces the time and effort required from operators to process samples and offers improved repeatability, safer lab operation, and increased productivity.  

ALH for FlowCam provides unattended analysis of up to 384 samples and is compatible with all new and existing  FlowCam 8000 series instruments, FlowCam LO, and FlowCam Cyano.  The ALH offers flexible hardware and a configurable deck platform that allow the instrument to meet each user's specific workflow requirements, including sample preparation such as mixing, dilution and heating/cooling, as well as instrument cleaning. 

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Topics: Protein Therapeutics, News and Events, FlowCam Technology, Biopharmaceutical Research

FlowCam Demonstrates Degradation of Protein Formulations After Transport in IV Bags via Hospital Pneumatic Tube System

Subvisible particles in biotherapeutics represent critical quality attributes because they pose regulatory and potential product safety risks. Therefore, much of the development work behind these therapeutics focuses on creating formulations and manufacturing processes that minimize the particle content in the drug product and reduce the potential for adverse immunogenicity. 

Pictured above are images of IV bags before and after transport via Pneumatic Tube System with Dextrose and Saline.

Despite measures taken during formulation and manufacturing, product quality can still be compromised after manufacturing due to accidental stresses caused by freeze-thawing, exposure to light, and mechanical shock from dropping the drug container. In a recent collaboration between the University of Colorado and Children's Hospital Colorado, researchers investigated particle generation in IV bags containing therapeutic protein formulations in the hospital's pneumatic tube system (PTS). Particle monitoring technologies like FlowCam are critical to ensure biotherapeutics have acceptable particle content not just after manufacturing but up until the therapy is administered to patients.

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Topics: Protein Therapeutics, Biopharmaceutical Research

FlowCam Measures Size of Zooplankton in China's Three Gorges Reservoir

Zooplankton are an essential part of the aquatic food web. They are the thread that connects the primary producers (phytoplankton) to high trophic organisms, and due to their small size are easily affected by changes in their environment. This makes them a good indicator of water quality and the effects of climate change on the health of water systems.

The Xiangxi Bay of the Three Gorges Reservoir in the Yichang region of China recently served as a place to observe these effects. The bay exhibits high spatial heterogeneity (or an uneven concentration of zooplankton species between different areas of the reservoir). It is this characteristic, likely resulting from variable nutrient levels, that made it a good place to study differences in zooplankton size spectrum and diversity as they relate to environmental factors.

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